Open SBIR and STTR solicitations
The Small Business Innovation Research and Small Business Technology Transfer programmes are the main route to non-dilutive federal funding for small companies doing research. Eleven agencies participate, each with its own priorities, cycles and topic lists.
The thing worth knowing when reading a list like this: the closing date is the least important column. What matters is whether your work answers the topic as written, and that question is best settled with the programme officer before you write anything.
7 opportunities
NSF Small Business Innovation Research / Small Business Technology Transfer Phase I, Phase II, Fast-Track Programs: A Pilot Emphasis on Scientific Instrumentation
U.S. National Science Foundation26-511
NewCloses 79 days left
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
National Institutes of HealthPA-27-102
NewCloses 231 days left
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)
National Institutes of HealthPA-27-100
NewCloses 231 days left
SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)
National Institutes of HealthPAR-27-098
NewCloses 962 days left
NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)
National Institutes of HealthPA-27-101
NewCloses 962 days left
NIEHS Worker Training Program’s SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed)
National Institutes of HealthTEMP-30794
NewNo fixed deadline
Forecast to Publish a Notice of Funding Opportunity for SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)
National Institutes of HealthFOR-CA-25-086
NewNo fixed deadline
Data from Grants.gov and SBIR.gov, refreshed daily. Listings link to the official notice, which is always authoritative — check dates and eligibility there before relying on anything here.